Different Terpene and Cannabinoid Combinations to Try

Different Terpene and Cannabinoid Combinations to Try

August 26, 2019

With researchers learning more about cannabis and its components than ever, is clear that CBD has a lot of potential medicinal benefits. Among these compounds—which include cannabinoids, like tetrahydrocannabinol (THC) and cannabidiol (CBD)— are terpenes, fragrant oils that have been found to have their own therapeutic effects. Discover what terpene and cannabinoid combinations you can try to enhance your next CBD experience.

Terpene and Cannabinoid Combinations You Should Try

Why combine different essential oils with CBD? Terpenes can help shape your experience or even enhance some of the pain-relieving and anxiety-reducing effects of CBD products; an effect often called the ‘entourage effect’. While the science behind terpenes and cannabinoids is still being researched, what we know so far paints a complicated picture. Let’s take a look at the science behind this fascinating phenomenon, and find out which combinations of terpenes and cannabinoids may be right for you.

But First: Understanding the Entourage Effect

Cannabis is an extremely diverse plant, which can lead to big differences in the way one cannabis product affects you relative to the next. From cannabinoids to terpenes, there are hundreds of different active compounds that may express themselves in any particular plant.

While research is still limited (and usually focused on the most plentiful cannabinoids and terpenes), there’s a fair bit of data coming out about the effects of these varying chemicals. We understand the basic effects of most cannabinoids and terpenes, and there’s information out there about these common chemical compounds.

But while many like to focus on the effects of individual cannabinoids or terpenes, the truth is even more complicated. These chemicals interact with each other in many different ways.

More than understanding what each chemical does on its own, it’s also important to understand the ways in which these chemicals interact with each other. This combining of chemical compounds is called the entourage effect, and its many different mixtures can be hard to track.

A common example of the entourage effect is the way that the terpene myrcene affects the cannabinoid THC. While THC is usually considered to have energetic effects, when mixed with enough myrcene, its effects become sedative and can lead to cannabis’s notorious couch-lock—when the consumer becomes too lethargic to move and feels stuck on the couch.

If you were just paying attention to the THC levels, and researching THC’s effects, you may think THC-rich cannabis would give you an energy boost. But the presence of myrcene flips the effect on its head and produces the opposite of what you were expecting. The lesson is that it’s crucially important to understand the many ways the entourage effect can alter cannabis’s medicinal outcomes.

Which Terpene-Cannabinoid Interactions Could Help Me?

While there’s a lot to learn about cannabinoid and terpene interactions, scientists have been studying the phenomenon and have noticed a few combinations with useful effects. One study, by cannabis researcher Dr. Ethan Russo highlights a few of the ways that cannabinoid and terpene combinations could be used for healing.

Here are five combinations of cannabinoids and terpenes that may help you:

1. Limonene and CBD Can Help Negate THC’s Poor Effect on Memory

It is not unusual for heavy cannabis users to report issues with their memory. It’s not surprising, as THC, the most common cannabinoid in cannabis, is known to cause some short- term memory issues. But, ancient wisdom and modern science point to a potential solution to this: citrus fruits These cannabis experts suggested that drinking lemonade or eating acidic fruits may allow patients to enjoy a cannabis treatment without the negative effects on memory.

More recently, as scientists have explored the benefits of terpenes, we’ve come to learn that this suggestion stemming from tenth century writings has more to do with limonene —a powerful terpene that’s present in both cannabis and citrus. For those trying to experience THC’s powerful medicinal properties without memory issues can try CBD products high in limonene like:

Select’s Lemon-Ginger CBD Tincture with Tumeric

Cannabella’s Lemon Lozenges

Sprig’s Lemon Tea CBD Soda Water

2. Linalool, Limonene & CBD Make a Good Combo to Help Combat Anxiety

CBD and Limonene can also pair well with linalool, a terpene commonly found in lavender, to help relieve anxiety. Research shows CBD, cannabis’s second-most plentiful cannabinoid, has the potential to greatly aid in reducing stress and creating feelings of calm and relaxation—and some terpenes may help boost this effect.

Both limonene and linalool are known to reduce anxiety, and, according to Dr. Russo, these terpenes may enhance the clinical efficacy of CBD. So, if you want to relax and unwind, find a linalool and limonene-rich CBD product to enjoy, and feel your stress melt away.


3. CGB & Pinene Work Together as an Antiseptic for MRSA

While cannabis is rarely looked at as a cure for infectious diseases, early research indicates that the combination of the terpene pinene and the cannabinoid cannabigerol (CBG) could help in treating Methicillin-resistant Staphylococcus aureus (MRSA).

MRSA is a bacterial infection that’s resistant to many of our antibiotic treatments. But research shows that CBG can inhibit MRSA. To add to this, other studies looking at pinene have found that a mixture containing 34.8% pinene was also effective against MRSA and other bacterial strains that are resistant to antibiotic treatments. Because of this, Dr. Russo’s study suggests that a combination of pinene and CBG could help combat this resistant infection. Consuming cannabis with CBG and pinene may also give your immune system a natural boost but we’re still a long way from understanding the full benefits of CBD, CBG, and other cannabinoids. Remember, if you believe you have MRSA or another kind of  infection, you head to your doctor right away.

4. Beta-Caryophyllene, Myrcene & Pinene Can Help CBD Fight Addiction

Addiction is a difficult cycle to break, but research suggests that CBD can aid in the process. As a nonaddictive cannabinoid that reduces pain, anxiety and depression, CBD can:

Help reduce the physical pain of withdrawal

Help replace addictive substances like painkillers or recreational drugs

Reduce substance cravings

Terpenes may also help even more in the fight against addiction? At least, according to the research. In one clinical trial, vapors from black pepper were shown to help significantly reduce nicotine cravings for cigarette smokers. We know that black pepper contains three terpenes, which may help aid in this process:

Beta-caryophyllene, which also may help reduce cravings by interacting with the CB2 receptor

Myrcene, which may increase sedation

Pinene, which boosts alertness and focus

Based on these findings, a high-CBD product with beta-caryophyllene, pinene and myrcene could make things a lot easier for those coping with addiction or going through withdrawals from an addictive medication.

limonene and beta-carophyllene

5. Topical CBD With Limonene, Pinene or Linalool for Acne

Acne is one of the most common problems for teens and adults, which makes this last synergistic combination a bit of a complexion clearing miracle. According to research, CBD oil may help slow down sebum production, which is one of the root causes of acne. Similarly, the terpenes limonene, linalool and pinene all have been shown to reduce acne–and in the case of limonene, even enhance the evenness of your skin tone. When used as a topical application, a combination of these terpenes and cannabinoids could help stop acne in its tracks in a natural and holistic way.

The cannabis flower is loaded with some incredible compounds. Cannabinoids and terpenes are just some of the compounds that affect the reception and experience of different CBD products.

Mix and Match with Terpenes and CBD

From CBD topicals, to CBD-infused food recipes, there are more options for mixing and matching with cannabinoids than ever. What CBD and terpene combinations are you curious to try?

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